Industrial Whey Utilization as a Medium Supplement for Biphasic Growth and Bacteriocin Production by Probiotic Lactobacillus casei LA-1.

摘要: The ability of probiotic Lactobacillus casei LA-1 for bacteriocin production using industrial by-products, such as whey, supplement in growth medium has been demonstrated the first time. Whey was investigated a sole carbon source cooperation with other components to substitute expensive nutrients MRS economical production. Industrial whey-supplemented then selected determine effect four variables (temperature, initial pH, incubation time, and whey concentration) by response surface methodology on Statistical analysis results showed that two have significant Response data maximum 6,132.33 AU/mL at an pH 7.12, temperature 34.29 °C, concentration 13.74 g/L. started during exponential phase, reaching values stationary biphasic pattern observed. Our current work demonstrates this approach utilization substitution costly great promise cost reduction industry novel biological metabolic product can be utilized food preservative.