Lung Cancer Detection and Characterization: Challenges and Solutions

摘要: The challenge of early detection and characterization lung cancer represents a persistent clinical problem reflecting the dire nature this malignancy. In United States alone, nearly 175 000 new cases are diagnosed yearly, which only 20-25% will be amenable to potential cure, with 5-year survival remaining less than 15% [10]. Although use routine chest radiography for screening has proved ineffective [19], recent technical developments have focused attention on CT screening, especially small peripheral tumors [12, 31]. These include: increasing availability multidetector (MDCT) scanners as many 10 16 detector rows; advanced image-processing workstations capable sophisticated image processing, including automatic nodule segmentation volume assessment; computerassisted diagnosis (CAD) analysis. While improving our ability detect lesions, not surprisingly, these technological provide us challenges opportunity develop innovative solutions.