ANGIOGENESIS, ANGIOGENIC GROWTH FACTORS AND DEVELOPMENT FACTORS
作者： P.A. D’Amore , M.K. Sakurai
DOI: 10.1016/B0-12-370879-6/00027-2
关键词: Mesenchymal stem cell 、 Respiratory distress 、 Early gestation 、 Respiratory system 、 Transforming growth factor 、 Biology 、 Cell biology 、 Vasculogenesis 、 Angiogenesis 、 Platelet-derived growth factor receptor 、 Immunology
摘要: Angiogenesis is crucial in pulmonary development to establish the groundwork structure for lungs’ main function of gas exchange across a thin blood barrier. This network and air conduits begins form early gestation continues through childhood, requiring intricate epithelial–mesenchymal interactions that are regulated by various angiogenic growth factors. Disruptions this complex system lead inadequate diseases respiratory distress. At time, precise roles these factors between epithelial mesenchymal cells poorly understood. A better understanding processes may improved therapies diseases.
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