Phase II trial of megestrol in the supportive care of patients receiving dose-intensive chemotherapy.

作者: Karsai H , Fetherstonhaugh Em , Knowling Ma , Osoba D , Mclaughlin Mj

DOI:

关键词: SucralfateMegestrol acetateWeight lossHead and neck cancerLung cancerPrednisoneMegestrolMedicineChemotherapyInternal medicine

摘要: Megestrol acetate was given daily to lung cancer patients undergoing therapy with CODE and recurrent head neck receiving DEB/M in an attempt prevent weight loss. The outcomes this study were compared the same similar groups of treated chemotherapy regimens, but which prednisone used as main supportive drug along co-trimoxazole, ketoconazole, either cimetidine or sucralfate. Weight loss less pronounced current than previous ones. Nevertheless, there several factors that led us conclude megestrol is not adequate substitute for kind chemotherapy.

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