Light phase-restricted feeding slows basal heart rate to exaggerate the type-3 long QT syndrome phenotype in mice.
作者： Elizabeth A. Schroder , Don E. Burgess , Cody L. Manning , Yihua Zhao , Arthur J. Moss
DOI: 10.1152/AJPHEART.00341.2014
关键词: Basal (phylogenetics) 、 Phenotype 、 Heart rate 、 QT interval 、 Long QT syndrome 、 Endocrinology 、 Long QT syndrome type 3 、 Biology 、 Internal medicine 、 Circadian rhythm
摘要: Long QT syndrome type 3 (LQT3) is caused by mutations in the SCN5A-encoded Nav1.5 channel. LQT3 patients exhibit time of day-associated abnormal increases their heart rate-corrected (QTc) int...
sci-hub.se 参考文章(38)
Dieter Nuyens, Milan Stengl, Saran Dugarmaa, Tom Rossenbacker, Veerle Compernolle, Yoram Rudy, Jos F. Smits, Willem Flameng, Colleen E. Clancy, Lieve Moons, Marc A. Vos, Mieke Dewerchin, Klaus Benndorf, Désiré Collen, Edward Carmeliet, Peter Carmeliet, Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome. Nature Medicine. ,vol. 7, pp. 1021- 1027 ,(2001) , 10.1038/NM0901-1021
Alexander A. Bachmanov, Danielle R. Reed, Gary K. Beauchamp, Michael G. Tordoff, Food Intake, Water Intake, and Drinking Spout Side Preference of 28 Mouse Strains Behavior Genetics. ,vol. 32, pp. 435- 443 ,(2002) , 10.1023/A:1020884312053
Ju-Yun Tsai, Petra C. Kienesberger, Thomas Pulinilkunnil, Mary H. Sailors, David J. Durgan, Carolina Villegas-Montoya, Anil Jahoor, Raquel Gonzalez, Merissa E. Garvey, Brandon Boland, Zachary Blasier, Tracy A. McElfresh, Vijayalakshmi Nannegari, Chi-Wing Chow, William C. Heird, Margaret P. Chandler, Jason R. B. Dyck, Molly S. Bray, Martin E. Young, Direct Regulation of Myocardial Triglyceride Metabolism by the Cardiomyocyte Circadian Clock Journal of Biological Chemistry. ,vol. 285, pp. 2918- 2929 ,(2010) , 10.1074/JBC.M109.077800
K. Eguchi, J. Ishikawa, S. Hoshide, T. G. Pickering, J. E. Schwartz, K. Shimada, K. Kario, Night time blood pressure variability is a strong predictor for cardiovascular events in patients with type 2 diabetes. American Journal of Hypertension. ,vol. 22, pp. 46- 51 ,(2009) , 10.1038/AJH.2008.294
Marek Malik, Velislav N Batchvarov, Measurement, interpretation and clinical potential of QT dispersion Journal of the American College of Cardiology. ,vol. 36, pp. 1749- 1766 ,(2000) , 10.1016/S0735-1097(00)00962-1
Judy F. Liu, Arthur J. Moss, Christian Jons, Jesaia Benhorin, Peter J. Schwartz, Carla Spazzolini, Lia Crotti, Michael J. Ackerman, Scott McNitt, Jennifer L. Robinson, Ming Qi, Ilan Goldenberg, Wojciech Zareba, Mutation-Specific Risk in Two Genetic Forms of Type 3 Long QT Syndrome American Journal of Cardiology. ,vol. 105, pp. 210- 213 ,(2010) , 10.1016/J.AMJCARD.2009.08.676
Jingjing Wu, Yanmin Zhang, Xinzhao Zhang, Longxian Cheng, Wim J. Lammers, Andrew A. Grace, James A. Fraser, Henggui Zhang, Christopher L. -H. Huang, Ming Lei, Altered sinoatrial node function and intra-atrial conduction in murine gain-of-function Scn5a+/ΔKPQ hearts suggest an overlap syndrome American Journal of Physiology-heart and Circulatory Physiology. ,vol. 302, ,(2012) , 10.1152/AJPHEART.00357.2011
VELISLAV BATCHVAROV, GANG YI, XIAOHUA GUO, IRINA SAVELIEVA, A. JOHN CAMM, MAREK MALIK, QT interval and QT dispersion measured with the threshold method depend on threshold level. Pacing and Clinical Electrophysiology. ,vol. 21, pp. 2372- 2375 ,(1998) , 10.1111/J.1540-8159.1998.TB01184.X
GRETCHEN WOLFF, KARYN A. ESSER, Scheduled exercise phase shifts the circadian clock in skeletal muscle. Medicine and Science in Sports and Exercise. ,vol. 44, pp. 1663- 1670 ,(2012) , 10.1249/MSS.0B013E318255CF4C
Deanna M. Arble, Joseph Bass, Aaron D. Laposky, Martha H. Vitaterna, Fred W. Turek, Circadian Timing of Food Intake Contributes to Weight Gain Obesity. ,vol. 17, pp. 2100- 2102 ,(2009) , 10.1038/OBY.2009.264