History of treatment for depression: risk factor for myocardial infarction in hypertensive patients.

摘要: OBJECTIVE Psychological factors have been suspected of contributing to the development cardiovascular disease. This study examined relationship between a self-reported history treatment for depression and subsequent myocardial infarction among treated hypertensive patients. METHODS Participants (5564) in union-sponsored, hypertension control program New York City, who entered during 1981-1994 without disease were asked whether they had depression, followed prospective cohort study. The primary outcome interest was hospitalization or death due infarction. RESULTS At entry, 3.5% men 6.4% women reported depression. During 4.9 years (average) follow-up, 112 fatal nonfatal infarctions recorded. sex-adjusted relative risk 2.24 (confidence interval = 1.13-4.45). Controlling known with multivariate proportional hazards models, significantly associated (hazard ratio 2.10, confidence 1.04-4.23). CONCLUSIONS A is independently patients prior Whether additional different will be cardioprotective unknown merits further