Efficacy of Contralateral Prophylactic Mastectomy in Women With a Personal and Family History of Breast Cancer

作者: Shannon K. McDonnell , Daniel J. Schaid , Jeffrey L. Myers , Clive S. Grant , John H. Donohue

DOI: 10.1200/JCO.2001.19.19.3938

关键词: ObstetricsMastectomyProphylactic MastectomyGynecologyContralateral Prophylactic MastectomyFamily historyBreast cancerBilateral Prophylactic MastectomyMedicineCohortCancer

摘要: PURPOSE: To estimate the efficacy of contralateral prophylactic mastectomy in women with a personal and family history breast cancer. PATIENTS AND METHODS: We followed course 745 first cancer and/or ovarian who underwent at Mayo Clinic between 1960 1993. Family information follow-up were obtained from medical record, study-specific questionnaire, telephone follow-up. Life-tables for cancers, which consider age cancer, current age, type history, used to calculate number cancers expected our cohort had they not mastectomy. RESULTS: Of cohort, 388 premenopausal (age < 50 years) 357 post- menopausal. Eight developed Six events observed among women, compared 106.2 predi...

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