Biomechanical Topography of Human Articular Cartilage in the First Metatarsophalangeal Joint

摘要: The objective of this study was to provide a map cartilage biomechanical properties, thickness, and histomorphometric characteristics in the human, cadaveric first metatarsophangeal joint, determine if normal articular predisposed topographically mismatches articulating surfaces. Cartilage intrinsic material properties thickness were obtained from seven pairs freshly frozen, cadaveric, metatarsophalangeal joints using an automated creep indentation apparatus under conditions biphasic creep. Eight sites tested: four on metatarsal head, two proximal phalanx base, one each sesamoid bone obtain aggregate modulus, Poisson's ratio, permeability, shear thickness. lateral site left head had largest modulus (1.34 MPa), whereas softest tissue found right medial (0.63 MPa). region joint most permeable (4.56 x 10(-15) meter4/Newton-second), articulation least (1.26 meter4/Newton-second). Material are indicative tissue's functional environment. lack surfaces may be supportive clinical observations that early degenerative changes, absence traumatic events, do not occur at selected test human joint.