JP8 exposure and neurocognitive performance among US Air Force personnel

摘要: Petroleum-based fuels such as jet propellant (JP) 4, JP5, JP8, and A1 (JetA) are among the most common occupational chemical exposures encountered by military civilian workforces. Although acute toxicity following high-level to JP8 similar mixtures has been reported, relationship between persistent low-level both longer-term central nervous system (CNS) function comparatively less well characterized. This paper describes results of neurocognitive assessments acquired repeatedly across a work week study design (Friday Friday) part Occupational Exposure Neuroepidemiology Study (OJENES) involving U.S. Air Force (AF) personnel with varying levels exposure fuel (JP8). were quantified using personal air monitoring urinary biomarkers exposure. Neurocognitive performance was evaluated an objective, standardized battery tests. No significant associations performances observed individuals having regular contact those minimal/no direct (measured average breathing zone exposure). Also, no findings noted repeated measures absorbed dose (multi-day pre-shift 1- 2-naphthol) reduced proficiency on tasks week. Results suggest that lower (than regulated standards) do not appear be associated acute, measurable differences or changes in performance.