Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation.
作者： Mark E Gurney , Haifeng Pu , Arlene Y Chiu , Mauro C Dal Canto , Cynthia Y Polchow
关键词: UBQLN2 、 Anatomy 、 Pathogenesis 、 Internal medicine 、 Genetically modified mouse 、 SOD1 、 Motor neuron 、 Superoxide dismutase 、 Amyotrophic lateral sclerosis 、 Mutation 、 Endocrinology 、 Biology
摘要: Mutations of human Cu,Zn superoxide dismutase (SOD) are found in about 20 percent of patients with familial amyotrophic lateral sclerosis (ALS). Expression of high levels of human …
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