TAT-mediated photochemical internalization results in cell killing by causing the release of calcium into the cytosol of cells
作者： Nandhini Muthukrishnan , Gregory A. Johnson , Jongdoo Lim , Eric E. Simanek , Jean-Philippe Pellois
DOI: 10.1016/J.BBAGEN.2012.06.020
关键词: Endocytosis 、 Organelle 、 Biochemistry 、 Cytosol 、 Endocytic cycle 、 Lysis 、 Endosome 、 Programmed cell death 、 Cell-penetrating peptide 、 Cell biology 、 Chemistry
摘要: Background Lysis of endocytic organelles is a necessary step in many cellular delivery methodologies. This achieved efficiently the photochemical internalization approach but cell death that accompanies this process remains problem.
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