Activation of SIRT1/PGC 1α/SIRT3 pathway by melatonin provides protection against mitochondrial dysfunction in isoproterenol induced myocardial injury.
作者： Shamreen Naaz , Sanatan Mishra , Palash K Pal , Aindrila Chattopadhyay , Asish R Das
DOI: 10.1016/J.HELIYON.2020.E05159
关键词: Pharmacology 、 Oxidative stress 、 Melatonin 、 SIRT3 、 Antioxidant 、 Reactive oxygen species 、 Mitochondrial biogenesis 、 Reperfusion injury 、 Catalase
摘要: … Preventing mitochondrial dysfunction and enhancing mitochondrial health and biogenesis is a … of melatonin protection of rat cardiac mitochondria against acute myocardial infarction. …
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