The Role of Complexed Prostate-Specific Antigen in Prostate Cancer Screening

作者: Matthew E. Nielsen , Alan W. Partin

DOI: 10.1007/978-1-60327-078-6_4

关键词: Prostate cancer screeningStandard careProstate-specific antigenProstate cancerInternal medicineOncologyTotal psaNomogramMedicineConfoundingFree psa

摘要: Complexed prostate-specific antigen (cPSA) testing has been shown to have greater specificity in detecting prostate cancer than total PSA testing. Factors supporting the use of cPSA measurement clinical screening include stability, longer half-life, less day-to-day variation, and variation setting confounding factors. Studies found that offers comparable perhaps superior performance percent free PSA. may also important predictive nomograms for pathologic staging patients with localized cancer. Investigation into uses critical implications future screening. The as a more specific method detection would reduce number biopsies performed overall cost To integrate standard care, standards guidelines are required.

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