Prospective study of alcohol drinking patterns and coronary heart disease in women and men
作者： Janne Tolstrup , Majken K Jensen , Tjønneland Anne , Kim Overvad , Kenneth J Mukamal
DOI: 10.1136/BMJ.38831.503113.7C
关键词: Confidence interval 、 Disease 、 Internal medicine 、 Hazard ratio 、 Lower risk 、 Medicine 、 Alcohol 、 Prospective cohort study 、 Surgery 、 Proportional hazards model 、 Incidence (epidemiology) 、 General Medicine
摘要: Objective To determine the association between alcohol drinking patterns and risk of coronary heart disease in women men. Design Population based cohort study. Setting Denmark, 1993-2002. Participants 28 448 25 052 men aged 50-65 years, who were free cardiovascular at entry to study. Main outcome measures Incidence occurring during a median follow-up period 5.7 years. Results 749 1283 events occurred among men. Women drank on least one day week had lower than less week. Little difference was found, however, frequency: (hazard ratio 0.64, 95% confidence interval 0.51 0.81), 2-4 days (0.63, 0.52 0.77), five or six (0.79, 0.61 1.03), seven (0.65, 0.84). For an inverse found frequency across entire range frequencies. The lowest observed daily (0.59, 0.48 0.71) compared with week. Conclusions Among intake may be primary determinant whereas men, frequency, not intake, seems more important.
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