Improved formulations with hydrophobic permeation enhancers

作者: Su Il Yum , Eun Soo Lee , Michel J-N. Cormier

DOI:

关键词: ChemistryPermeationEnhancerLag timeChromatographyActive agentIrritationPermeability (electromagnetism)Combinatorial chemistryBiological activity

摘要: This invention is directed to a novel formulation for effectively utilizing hydrophobic permeation enhancers the increased permeability of active agents through skin or mucosa along with reduction lag time between application agent and attainment therapeutically effective flux, little no irritation host. The compositions containing enhancer, which enhancer has been micronized stabilized in an inert carrier such as water. These can be combined biologically provide enhanced mucosa.

参考文章(1)
Hans Dr. Röchling, Karlheinrich Dr. Schmid, Dieter Dr. Düwel, Pour-on formulation for application of anthelminthics ,(1992)