作者: Su Il Yum , Eun Soo Lee , Michel J-N. Cormier
DOI:
关键词: Chemistry 、 Permeation 、 Enhancer 、 Lag time 、 Chromatography 、 Active agent 、 Irritation 、 Permeability (electromagnetism) 、 Combinatorial chemistry 、 Biological activity
摘要: This invention is directed to a novel formulation for effectively utilizing hydrophobic permeation enhancers the increased permeability of active agents through skin or mucosa along with reduction lag time between application agent and attainment therapeutically effective flux, little no irritation host. The compositions containing enhancer, which enhancer has been micronized stabilized in an inert carrier such as water. These can be combined biologically provide enhanced mucosa.