Isolated monoclonal antibody or antigen-binding fragment that cleaves octanoylated native ghrelin
作者： Victor Raso
DOI:
关键词: Biology 、 Ghrelin 、 Enzyme 、 Appetite 、 Antigen Binding Fragment 、 Monoclonal antibody 、 Cleave 、 Antibody 、 Biochemistry
摘要: The present invention relates, in part, to agents for binding and/or inactivating native ghrelin. These include those that specifically bind cleave octanoylated Such antibodies and enzymes. also can be used generate Compositions the are provided. Further provided methods of producing using compositions thereof. For instance, reduce or eliminate hunger response activity Therefore, agents, suppress appetite treat obesity. In addition, any disease associated with caused by ghrelin (e.g., Prader-Willi Syndrome).
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