A staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice
作者： Juliane Bubeck Wardenburg , Hironori Mikumo , Karen Frank , Yuichi Mizuta , Georgia Wilke
DOI:
关键词: Cadherin 、 Receptor 、 Pathogenesis 、 Microbiology 、 Metalloprotease inhibitor 、 Metalloproteinase 、 Lung injury 、 Knockout mouse 、 Immunology 、 Biology 、 Adherens junction
摘要: … As epithelial barrier integrity is disrupted in pneumonia, we hypothesized that ADAM10 enzymatic activity may contribute to toxin-mediated injury. To assess whether Hla alters ADAM10 …
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