Influence of breast versus formula milk on physiological gastroesophageal reflux in healthy, newborn infants.

摘要: The effect of milk type on physiological, gastroesophageal reflux (GER) was studied in 37 breast-fed and formula-fed, healthy, term neonates aged 2-8 days. were randomly selected from the public maternity ward for 4 h after their morning feed. GER recorded by a pH microelectrode placed 6 cm above junction analyzed third fourth postprandial hours. Sleep state accurately defined electroencephalogram, electrooculogram, electromyogram, breathing, behavioral observations. Movement piezo-electric transducer. In active sleep, demonstrated episodes significantly shorter duration than formula-fed neonates. means 95% confidence intervals (CI) 3.0 (1.6,5.2) compared with 8.3 (5.0,13.3) min/h sleep respectively (p less 0.05). This could not be explained greater volume or increased movement before during However, lower median values neonates, 2.0 versus 2.5, different difference may reflect more rapid gastric emptying. esophageal is likely to stimulate peristalsis thus limit (shorter episodes),