Distinct and redundant expression and transcriptional diversity of MEIS gene paralogs during chicken development.

作者: Luis Óscar Sánchez-Guardado , Manuel Irimia , Luisa Sánchez-Arrones , Demián Burguera , Lucía Rodríguez-Gallardo

DOI: 10.1002/DVDY.22621

关键词: Transcription factorBiologyMorphogenesisGeneticsGeneGastrulationMesodermHomeoboxAlternative splicingGenome

摘要: Members of the Meis family TALE homeobox transcription factors are involved in many processes vertebrate development and morphogenesis, showing extremely complex transcriptional spatiotemporal expression patterns. In this work, we performed a comprehensive study chicken genes using multiple approaches. First, assessed whether genome contains Meis3 ortholog or harbors only two genes; gathered several lines evidence pointing to specific loss an early ancestor birds. Next, studied diversity generated from through alternative splicing during development. Finally, detailed analysis chick Meis1/2 patterns embryogenesis organogenesis. We show that both begins at gastrulation stage three embryonic layers, presenting highly dynamic with overlapping as well distinct domains throughout Developmental Dynamics 240:1475–1492, 2011. © 2011 Wiley-Liss, Inc.

参考文章(84)
Liana F Lareau, Richard E Green, Rajiv S Bhatnagar, Steven E Brenner, The evolving roles of alternative splicing. Current Opinion in Structural Biology. ,vol. 14, pp. 273- 282 ,(2004) , 10.1016/J.SBI.2004.05.002
Seong-Kyu Choe, Nikolaos Vlachakis, Charles G. Sagerstrom, Meis3 synergizes with Pbx4 and Hoxb1b in promoting hindbrain fates in the zebrafish. Development. ,vol. 128, pp. 1299- 1312 ,(2001) , 10.1242/DEV.128.8.1299
Dale Frank, Charna Dibner, Sarah Elias, XMeis3 protein activity is required for proper hindbrain patterning in Xenopus laevis embryos. Development. ,vol. 128, pp. 3415- 3426 ,(2001) , 10.1242/DEV.128.18.3415
Luis Óscar Sánchez-Guardado, José Luis Ferran, Lucía Rodríguez-Gallardo, Luis Puelles, Matías Hidalgo-Sánchez, Meis gene expression patterns in the developing chicken inner ear. The Journal of Comparative Neurology. ,vol. 519, pp. 125- 147 ,(2011) , 10.1002/CNE.22508
Tomoyuki Hisa, Sally E Spence, Rivka A Rachel, Masami Fujita, Takuro Nakamura, Jerrold M Ward, Deborah E Devor-Henneman, Yuriko Saiki, Haruo Kutsuna, Lino Tessarollo, Nancy A Jenkins, Neal G Copeland, Hematopoietic, angiogenic and eye defects in Meis1 mutant animals. The EMBO Journal. ,vol. 23, pp. 450- 459 ,(2004) , 10.1038/SJ.EMBOJ.7600038
Yakop Jacobs, Catherine A. Schnabel, Michael L. Cleary, Trimeric Association of Hox and TALE Homeodomain Proteins Mediates Hoxb2 Hindbrain Enhancer Activity Molecular and Cellular Biology. ,vol. 19, pp. 5134- 5142 ,(1999) , 10.1128/MCB.19.7.5134
Rotem Sorek, Ron Shamir, Gil Ast, How prevalent is functional alternative splicing in the human genome Trends in Genetics. ,vol. 20, pp. 68- 71 ,(2004) , 10.1016/J.TIG.2003.12.004
Rami A Dalloul, Julie A Long, Aleksey V Zimin, Luqman Aslam, Kathryn Beal, Le Ann Blomberg, Pascal Bouffard, David W Burt, Oswald Crasta, Richard PMA Crooijmans, Kristal Cooper, Roger A Coulombe, Supriyo De, Mary E Delany, Jerry B Dodgson, Jennifer J Dong, Clive Evans, Karin M Frederickson, Paul Flicek, Liliana Florea, Otto Folkerts, Martien AM Groenen, Tim T Harkins, Javier Herrero, Steve Hoffmann, Hendrik-Jan Megens, Andrew Jiang, Pieter de Jong, Pete Kaiser, Heebal Kim, Kyu-Won Kim, Sungwon Kim, David Langenberger, Mi-Kyung Lee, Taeheon Lee, Shrinivasrao Mane, Guillaume Marcais, Manja Marz, Audrey P McElroy, Thero Modise, Mikhail Nefedov, Cédric Notredame, Ian R Paton, William S Payne, Geo Pertea, Dennis Prickett, Daniela Puiu, Dan Qioa, Emanuele Raineri, Magali Ruffier, Steven L Salzberg, Michael C Schatz, Chantel Scheuring, Carl J Schmidt, Steven Schroeder, Stephen MJ Searle, Edward J Smith, Jacqueline Smith, Tad S Sonstegard, Peter F Stadler, Hakim Tafer, Zhijian Tu, Curtis P Van Tassell, Albert J Vilella, Kelly P Williams, James A Yorke, Liqing Zhang, Hong-Bin Zhang, Xiaojun Zhang, Yang Zhang, Kent M Reed, None, Multi-Platform Next-Generation Sequencing of the Domestic Turkey (Meleagris gallopavo): Genome Assembly and Analysis PLOS Biology. ,vol. 8, pp. 275- 281 ,(2010) , 10.1371/JOURNAL.PBIO.1000475
Jakob Lewin Rukov, Manuel Irimia, Søren Mørk, Viktor Karlovich Lund, Jeppe Vinther, Peter Arctander, High Qualitative and Quantitative Conservation of Alternative Splicing in Caenorhabditis elegans and Caenorhabditis briggsae Molecular Biology and Evolution. ,vol. 24, pp. 909- 917 ,(2007) , 10.1093/MOLBEV/MSM023
S. D'Aniello, M. Irimia, I. Maeso, J. Pascual-Anaya, S. Jimenez-Delgado, S. Bertrand, J. Garcia-Fernandez, Gene Expansion and Retention Leads to a Diverse Tyrosine Kinase Superfamily in Amphioxus Molecular Biology and Evolution. ,vol. 25, pp. 1841- 1854 ,(2008) , 10.1093/MOLBEV/MSN132