Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling.

作者: Y Feng , C Ke , Q Tang , H Dong , X Zheng

DOI: 10.1038/CDDIS.2014.59

关键词: STAT3Signal transductionCell biologyAutophagyCancer researchSmall interfering RNAMetforminSTAT proteinApoptosisBiologyCell growth

摘要: … of Stat3 signaling in autophagy in metformin-treated ESCC cells, we characterized the effects of metformin in cells in which Stat3 … In line with metformin treatment, knockdown of Stat3 not …

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