作者: Sang Yong Jon , Narayanan Selvapalam , Dong Hyun Oh , Jin-Koo Kang , Soo-Young Kim
DOI: 10.1021/JA036536C
关键词: Solubility 、 Chemical stability 、 Cucurbituril 、 Organic synthesis 、 Hildebrand solubility parameter 、 Stereochemistry 、 Peptide drug 、 Chemistry 、 Surface modification
摘要: A long-standing problem in cucurbituril chemistry is answered through the first direct functionalization of cucurbit[n]uril (CB[n]; n = 5-8)) leading to perhydroxyCB[n] which can be further modified provide tailored CB[n] derivatives with desired functional groups and good solubility. Anchoring a CB[6] derivative on surface its potential application as sensor are demonstrated. forms nanospheres possible use protein peptide drug delivery.