Water-insoluble, nanocrystalline, and hydrogel fibrillar scaffolds for biomedical applications

摘要: Recently, micro/nanofibrillar materials have been widely utilized for a variety of applications in many different fields research due to their relatively large surface-to-volume ratios, high porosity, and three-dimensional connectivity, along with cost-effective fabrication processes. Herein, we present review recent progress the development scaffolds specific focus on biomedical applications. From perspective controlling polymer–polymer polymer–water molecular interactions, categorized fibrillar into insoluble, nanocrystalline, hydrogel fibers. Based our studies related this topic, provide significance essential information four scaffolds: (1) solid based water-insoluble polymers, (2) nanofibrillar network crystalline bacterial cellulose, (3) micro/nanofiber partially precipitated PVA, (4) chemically cross-linked PVA. The discussion should guidance researchers selecting scaffold suitable own purposes help inspire them develop more sophisticated future. We reviewed demonstrated This would guide proper developing scaffolds.