3 : 3′-Diamidinocarbanilide: a New Drug Active against Babesial Infections

作者: J. N. ASHLEY , S. S. BERG , J. M. S. LUCAS

DOI: 10.1038/185461A0

关键词: BabesiasisPentamidineDrugSingle injectionStimulationPharmacologyPhenamidineMedicine

摘要: QUINURONIUM sulphate1is the commonly employed treatment for British bovine redwater and a single injection of 1 mgm. this drug per kgm. body-weight is effective in high proportion cases. But quinuronium sulphate has disadvantage that even therapeutic doses it produces toxic effects associated with parasympathetic stimulation. The diamidines, phenamidine pentamidine, as their di-isethionates, Berenil are well tolerated also used babesiasis, but they less active than sulphate.

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