Rapid uptake of glucose and lactate, and not hypoxia, induces apoptosis in three-dimensional tumor tissue culture

作者: Rachel W. Kasinskas , Raja Venkatasubramanian , Neil S. Forbes

DOI: 10.1039/C4IB00001C

关键词: MetabolismIntracellularBiochemistryCell cultureApoptosisCell biologyProgrammed cell deathGlutamineBiologyLactic acidCarbohydrate metabolism

摘要: … saturated; oxygen uptake was limited by intracellular metabolism; and oxygen uptake was not limited by membrane-transport or diffusion. Unsaturated transmembrane uptake may be …

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