Identification of biomarkers associated with diagnosis and prognosis of colorectal cancer patients based on integrated bioinformatics analysis

作者: Linbo Chen , Dewen Lu , Keke Sun , Yuemei Xu , Pingping Hu

DOI: 10.1016/J.GENE.2019.01.001

关键词: R softwareMicroarray analysis techniquesReceiver operating characteristicBioinformatics analysisComputational biologyGene signatureColorectal cancerGeneBiologyMMP1

摘要: … study aimed to identify potential diagnostic and prognostic gene biomarkers for colorectal … genes from the common DEGs by constructing protein-protein interaction (PPI) network. The …

参考文章(43)
Graeme Milligan, Evi Kostenis, Heterotrimeric G-proteins: a short history British Journal of Pharmacology. ,vol. 147, ,(2006) , 10.1038/SJ.BJP.0706405
Dmitri Mouradov, Oliver M. Sieber, Richard J. Simpson, Agus Salim, Antony Bacic, Andrew F. Hill, David A. Stroud, Michael T. Ryan, Johnson I. Agbinya, John M. Mariadason, Antony W. Burgess, Suresh Mathivanan, Mohashin Pathan, Shivakumar Keerthikumar, Ching-Seng Ang, Lahiru Gangoda, Camelia Y.J. Quek, Nicholas A. Williamson, FunRich: An open access standalone functional enrichment and interaction network analysis tool PROTEOMICS. ,vol. 15, pp. 2597- 2601 ,(2015) , 10.1002/PMIC.201400515
Irfan M. Hisamuddin, Vincent W. Yang, Molecular Genetics of Colorectal Cancer: An Overview. Current Colorectal Cancer Reports. ,vol. 2, pp. 53- 59 ,(2006) , 10.1007/S11888-006-0002-2
Jo Vandercappellen, Jo Van Damme, Sofie Struyf, The role of CXC chemokines and their receptors in cancer Cancer Letters. ,vol. 267, pp. 226- 244 ,(2008) , 10.1016/J.CANLET.2008.04.050
Kathrin Rupertus, Janine Sinistra, Claudia Scheuer, Ruth M. Nickels, Martin K. Schilling, Michael D. Menger, Otto Kollmar, Interaction of the chemokines I-TAC (CXCL11) and SDF-1 (CXCL12) in the regulation of tumor angiogenesis of colorectal cancer. Clinical & Experimental Metastasis. ,vol. 31, pp. 447- 459 ,(2014) , 10.1007/S10585-014-9639-4
M Itakura, Y Terashima, M Shingyoji, S Yokoi, M Ohira, H Kageyama, Y Matui, Y Yoshida, H Ashinuma, Y Moriya, H Tamura, K Harigaya, K Matushima, T Iizasa, A Nakagawara, H Kimura, High CC chemokine receptor 7 expression improves postoperative prognosis of lung adenocarcinoma patients. British Journal of Cancer. ,vol. 109, pp. 1100- 1108 ,(2013) , 10.1038/BJC.2013.440
Mikio Kawamura, Yuji Toiyama, Kouji Tanaka, Susumu Saigusa, Yoshinaga Okugawa, Junichiro Hiro, Keiichi Uchida, Yasuhiko Mohri, Yasuhiro Inoue, Masato Kusunoki, CXCL5, a promoter of cell proliferation, migration and invasion, is a novel serum prognostic marker in patients with colorectal cancer European Journal of Cancer. ,vol. 48, pp. 2244- 2251 ,(2012) , 10.1016/J.EJCA.2011.11.032
Vanesa G Martinez, Lorraine O'Driscoll, Neuromedin U: A Multifunctional Neuropeptide with Pleiotropic Roles Clinical Chemistry. ,vol. 61, pp. 471- 482 ,(2015) , 10.1373/CLINCHEM.2014.231753
Florian Hohla, Stefan Buchholz, Andrew V. Schally, Awtar Krishan, Ferenc G. Rick, Luca Szalontay, Andrea Papadia, Gabor Halmos, Frank Koster, Elmar Aigner, Christian Datz, Stephan Seitz, Targeted cytotoxic somatostatin analog AN-162 inhibits growth of human colon carcinomas and increases sensitivity of doxorubicin resistant murine leukemia cells. Cancer Letters. ,vol. 294, pp. 35- 42 ,(2010) , 10.1016/J.CANLET.2010.01.018