Concordance of electrocardiographic and scintigraphic criteria of myocardial injury after cardiac surgery

作者: Milton S. Klein , R. Edward Coleman , Clarence S. Weldon , Burton E. Sobel , Robert Roberts

DOI: 10.1016/S0022-5223(19)40135-9

关键词: Myocardial infarction diagnosisInfarctionMedicineCoronary artery bypass surgeryBypass surgeryCardiac surgeryInternal medicineCardiologyCoronary artery diseasePerioperativeMyocardial infarction

摘要: The concordance of transmural electrocardiographic (ECG) changes and myocardial infarct imaging in detecting injury the perioperative period was evaluated 50 patients undergoing coronary artery bypass surgery 6 without disease valve replacement. Scintigraphy with technetium-99m (Sn) labeled pyrophosphate performed 3 to 7 days after surgery. Plasma creatine phosphokinase (CPK) levels were determined preoperatively daily for postoperatively. MB-CPK assayed fluorometrically samples obtained at 12 hour intervals 36 hours. Total CPK concentrations normal all but increased every patient A total 8 (16%) had evidence infarction. Six these (12%) exhibited abnormal images surgery, associated ECG each case. other 2 (4%) who among 4 developed bundle branch block operation. Abnormal did not occur any replacement despite elevations. These results indicate that elevations consistently cardiac cannot be relied upon detection Furthermore, new conduction defects may necessarily a sign infarction, useful means establishing infarction this group patients.

参考文章(12)
S B Rosalki, An improved procedure for serum creatine phosphokinase determination. Journal of Laboratory and Clinical Medicine. ,vol. 69, pp. 696- 705 ,(1967) , 10.5555/URI:PII:0022214367901795
Robert Roberts, Philip D. Henry, Sake A.G.J. Witteeveen, Burton E. Sobel, Quantification of serum creatine phosphokinase isoenzyme activity. American Journal of Cardiology. ,vol. 33, pp. 650- 654 ,(1974) , 10.1016/0002-9149(74)90257-4
ROBERT W. PARKEY, FREDERICK J. BONTE, STEVEN L. MEYER, JAMES M. ATKINS, GEORGE L. CURRY, ERNEST M. STOKELY, JAMES T. WILLERSON, A New Method for Radionuclide Imaging of Acute Myocardial Infarction in Humans Circulation. ,vol. 50, pp. 540- 546 ,(1974) , 10.1161/01.CIR.50.3.540
SEWELL H. DIXON, LEE E. LIMBIRD, CHARLES R. ROE, GALEN S. WAGNER, H. NEWLAND OLDHAM, DAVID C. SABISTON, Recognition of Postoperative Acute Myocardial Infarction Application of Isoenzyme Techniques Circulation. ,vol. 48, ,(1973) , 10.1161/01.CIR.48.1S3.III-137
Melvin R. Platt, Frederick J. Bonte, William Shapiro, Winfred L. Sugg, Robert W. Parkey, James T. Willerson, Technetium Stannous Pyrophosphate Myocardial Scintigrams in the Recognition of Myocardial Infarction in Patients Undergoing Coronary Artery Revascularization The Annals of Thoracic Surgery. ,vol. 21, pp. 311- 317 ,(1976) , 10.1016/S0003-4975(10)64318-4
DAVID L. BREWER, ROBERT H. BILBRO, ALAN G. BARTEL, Myocardial Infarction as a Complication of Coronary Bypass Surgery Circulation. ,vol. 47, pp. 58- 64 ,(1973) , 10.1161/01.CIR.47.1.58
Malcolm R. Rose, Ephraim Glassman, O.Wayne Isom, Frank C. Spencer, Electrocardiographic and serum enzyme changes of myocardial infarction after coronary artery bypass surgery. American Journal of Cardiology. ,vol. 33, pp. 215- 220 ,(1974) , 10.1016/0002-9149(74)90277-X
EDWIN L. ALDERMAN, HARVEY J. MATLOF, NORMAN E. SHUMWAY, DONALD C. HARRISON, Evaluation of Enzyme Testing for the Detection of Myocardial Infarction Following Direct Coronary Surgery Circulation. ,vol. 48, pp. 135- 140 ,(1973) , 10.1161/01.CIR.48.1.135
J T Willerson, R W Parkey, F J Bonte, S L Meyer, E M Stokely, Acute subendocardial myocardial infarction in patients. Its detection by Technetium 99-m stannous pyrophosphate myocardial scintigrams. Circulation. ,vol. 51, pp. 436- 441 ,(1975) , 10.1161/01.CIR.51.3.436