Bicyclic compounds useful as gpr120 modulators

作者: Brian Raimundo , John Griffin , Eric Stangeland , Elena S. Koltun

DOI:

关键词: GPR120ChemistryCombinatorial chemistryBicyclic molecule

摘要: Provided herein are compounds, compositions including them, and methods of modulating GPR120 activity treating diseases mediated by administering such compounds compositions.

参考文章(34)
Elemer Moczar, Ladislas Robert, Christiane Marie-Pierre Kerneur, William Georges Hornebeck, Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors ,(1991)
Mario Mezler, Katja Jantos, Wilfried Braje, Margaretha Henrica Maria Bakker, Jayne Froggett, Hervé Geneste, Novel small molecule potentiators of metabotropic glutamate receptors i ,(2011)
Kunyong Yang, Xiaohui He, Xuefeng Zhu, Hong Liu, Robert Epple, Compounds and methods for modulating g protein-coupled receptors ,(2009)
Graham Johnson, John M. McCall, Keith D. Barnes, Jill Heemskerk, David Fairfax, Matthew Robert Johnson, Compounds for the treatment of spinal muscular atrophy and other uses ,(2007)
Masahiro Sakaitani, Ikumi Hyoudoh, Noriyuki Furuichi, Hitoshi Iikura, Toshiyuki Sakai, Sawako Ozawa, Yasushi Tomii, Kenji Takanashi, Masayuki Matsushita, Toshihiro Aoki, Naoki Harada, Fumio Watanabe, Pil-Su Ho, p27 PROTEIN INDUCER ,(2008)
Dieter Wolfgang Hamprecht, Kamal A. Al-Barazanji, Sula Anne Armstrong, Martin Jones, Mohammad Tadayyon, David Richard Witty, Lactam derivatives as antagonists for human 11cby receptors ,(2002)
Jayaraman Selvakumar, Ramana Sreenivasa Rao, Vijayan Srinivasapriyan, Srinivasan Marutheeswaran, Chinnasamy Ramaraj Ramanathan, Synthesis of Condensed Tetrahydroisoquinoline Class of Alkaloids by Employing TfOH‐Mediated Imide Carbonyl Activation European Journal of Organic Chemistry. ,vol. 2015, pp. 2175- 2188 ,(2015) , 10.1002/EJOC.201403617
Christopher Joseph Sinz, Mariappan Chelliah, Keith Eagen, John S Debenham, Unmesh Shah, Clare London, Jason M. Cox, Henry M. Vaccaro, Zhongxiang Sun, Hong Dong Chu, Michael A. Plotkin, Skikanth Venkatraman, Ping Lan, Substituted spiropiperidinyl compounds useful as gpr120 agonists ,(2013)
Dennis M. Roland, John H. Van Duzer, Indolyl substituted hydroxylamine derivatives ,(1993)
Zhihua Sui, Michael P. Winters, Bicyclic pyrrole derivatives useful as agonists of gpr120 ,(2014)