Pros and cons of bifunctional platinum(IV) antitumor prodrugs: two are (not always) better than one

作者: Elisabetta Gabano , Mauro Ravera , Domenico Osella

DOI: 10.1039/C4DT00911H

关键词: ProdrugBioactive moleculesBifunctionalStereochemistryChemistryPlatinum

摘要: … Mitochondria provide energy for various cellular activities and mitochondrial disorders are related to many kinds of diseases. Due to the enhanced glycolytic metabolism of cancer cells (…

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