Early- and medium-term results after aortic arch replacement with frozen elephant trunk techniques-a single center study.

作者: Martin Misfeld , David Holzhey , Christian D. Etz , Friedrich W. Mohr , Piroze Daviewala

DOI: 10.3978/J.ISSN.2225-319X.2013.09.22

关键词: ParaplegiaComplicationStrokeSurgeryMortality rateSingle CenterMedicinePerioperativeElephant trunksSpinal cord injury

摘要: Background: The treatment of patients with extensive thoracic aortic disease involving the arch and descending thoracic/thoracoabdominal aorta is often performed using frozen elephant trunk technique (FET). We retrospectively analyzed our results FET operation. Methods: A total 51 consecutive underwent surgery between January 2006 August 2013. For all patients, E-vita hybrid open stent-graft (Jotec, Hechingen, Germany) was used. had a mean age 64±13 years, 51.1% being female. Degenerative or atherosclerotic aneurysm indication for in 62.7% patients. Another 15.7% 13.7% suffered from acute Type A, B dissection, respectively. Results: in-hospital 30-day mortality 7.8%. Stroke occurred 11.8% (n=6), new-onset paraplegia 19.6% (n=10) core body temperature ≥28 ℃ during circulatory arrest, combination prolonged arrest time more than 45 minutes, an independent predictor permanent spinal cord injury [odds ratios (OR), 4.8; 95% confidence intervals (CI), 1.1-21; P=0.04]. estimated 1- 5-year survival (80.2±5.5)% (59.7±10.2)%, respectively, 3.4±0.4 years. freedom endovascular intervention 4.2±0.4 unadjusted repair (TEVAR) (84.9±5.9)% (69.2±11.2)%, Conclusions: procedure associated acceptable early medium term rate. This high incidence perioperative injury. In order to prevent above complication, deep hypothermia strongly recommended expected time.

参考文章(16)
K Tsagakis, P Oberwalder, R Di Bartolomeo, M Grabenwoger, H Jakob, S Cerny, D Pacini, F Mohr, R Bonser, C Mestres, The International E-vita Open Registry: data sets of 274 patients. Journal of Cardiovascular Surgery. ,vol. 52, pp. 717- 723 ,(2011)
Jorge Flores, Takashi Kunihara, Norihiko Shiiya, Kimihiro Yoshimoto, Kenji Matsuzaki, Keishu Yasuda, Extensive deployment of the stented elephant trunk is associated with an increased risk of spinal cord injury. The Journal of Thoracic and Cardiovascular Surgery. ,vol. 131, pp. 336- 342 ,(2006) , 10.1016/J.JTCVS.2005.09.050
Nawid Khaladj, Malakh Shrestha, Sara Meck, Sven Peterss, Hiroyuki Kamiya, Klaus Kallenbach, Michael Winterhalter, Ludwig Hoy, Axel Haverich, Christian Hagl, Hypothermic circulatory arrest with selective antegrade cerebral perfusion in ascending aortic and aortic arch surgery: a risk factor analysis for adverse outcome in 501 patients. The Journal of Thoracic and Cardiovascular Surgery. ,vol. 135, pp. 908- 914 ,(2008) , 10.1016/J.JTCVS.2007.07.067
Scott A. LeMaire, Stacey A. Carter, Joseph S. Coselli, The elephant trunk technique for staged repair of complex aneurysms of the entire thoracic aorta. The Annals of Thoracic Surgery. ,vol. 81, pp. 1561- 1569 ,(2006) , 10.1016/J.ATHORACSUR.2005.11.038
Lee J. Goldstein, Ryan R. Davies, John A. Rizzo, Javier J. Davila, Matthew R. Cooperberg, Richard K. Shaw, Gary S. Kopf, John A. Elefteriades, Stroke in surgery of the thoracic aorta: Incidence, impact, etiology, and prevention The Journal of Thoracic and Cardiovascular Surgery. ,vol. 122, pp. 935- 945 ,(2001) , 10.1067/MTC.2001.117276
Martin Misfeld, Sergey Leontyev, Michael A. Borger, Olivier Gindensperger, Sven Lehmann, Jean-Francois Legare, Friedrich W. Mohr, What Is the Best Strategy for Brain Protection in Patients Undergoing Aortic Arch Surgery? A Single Center Experience of 636 Patients The Annals of Thoracic Surgery. ,vol. 93, pp. 1502- 1508 ,(2012) , 10.1016/J.ATHORACSUR.2012.01.106
Takeshi Miyairi, Yutaka Kotsuka, Masahiko Ezure, Minoru Ono, Tetsuro Morota, Hiroshi Kubota, Ko Shibata, Katsuhito Ueno, Shinichi Takamoto, Open stent-grafting for aortic arch aneurysm is associated with increased risk of paraplegia The Annals of Thoracic Surgery. ,vol. 74, pp. 83- 89 ,(2002) , 10.1016/S0003-4975(02)03602-0
Franz F. Immer, Barbara Moser, Eva S. Krähenbühl, Lars Englberger, Mario Stalder, Friedrich S. Eckstein, Thierry Carrel, Arterial access through the right subclavian artery in surgery of the aortic arch improves neurologic outcome and mid-term quality of life. The Annals of Thoracic Surgery. ,vol. 85, pp. 1614- 1618 ,(2008) , 10.1016/J.ATHORACSUR.2007.11.027
H. Borst, G. Walterbusch, D. Schaps, Extensive aortic replacement using "elephant trunk" prosthesis Thoracic and Cardiovascular Surgeon. ,vol. 31, pp. 37- 40 ,(1983) , 10.1055/S-2007-1020290