An Electrically-Driven Rotary Blood Pump Based on the Wankel Engine

作者: Norimasa Mitsui , Patrick Havlik , Thierry Mesana , Jean Trinkl , Jean-Luc Tourres

DOI: 10.1007/978-4-431-67023-0_37

关键词: Biomedical engineeringBlood pumpRotor (electric)Direct currentWankel engineVentricular assist deviceMaterials scienceDC motorPower (physics)Pistonless rotary engine

摘要: Our laboratory is developing an implantable electrically-driven left ventricular assist device. The device consists of a rotary pump coupled with brushless direct current (DC) motor. pump, which based on the Wankel engine principle and composed elliptically-shaped rotor housing, produces semi-pulsatile flow without valves. DC motor directly drives shaft at low speeds ranging from 20 to 180 rotations per min (rpm). pump-motor unit connected external power control by thin electric cable. titanium alloy prototype has stroke volume 60 cm3 able deliver mean over 81/min. In vivo experiments have been performed. Four lasted longer than 10 days (maximum 13 days) two for 6 days. Moderate hemolysis initial decrease in platelet count were observed. Further improvement will be necessary permit long-term use reduce adverse effects blood cells.

参考文章(9)
Aufiero Tx, Pae We, Miller Ca, Mehta Sm, Pierce Ws, Combined Registry for the Clinical Use of Mechanical Ventricular Assist Pumps and the Total Artificial Heart in conjunction with heart transplantation: sixth official report--1994. Journal of Heart and Lung Transplantation. ,vol. 14, pp. 585- 593 ,(1995)
Harasaki H, Jacobs G, Tsutsui T, Nosé Y, Golding L, Sutton C, Idioperipheral pulsation during nonpulsatile biventricular bypass experiments. Asaio Journal. ,vol. 32, pp. 263- 268 ,(1986)
Yozu R, Taguchi S, Soma Y, Iseki H, Inoue T, Effects of nonpulsatile and pulsatile right ventricular bypass on pulmonary circulation. Asaio Journal. ,vol. 34, pp. 213- ,(1988)
P Havlik, J Trinkl, T Mesana, T Gauthier, F Aucomte, J R Monties, Rotary pump artificial heart: a new system for circulatory assistance or heart replacement. Life support systems : the journal of the European Society for Artificial Organs. ,vol. 5, pp. 251- 257 ,(1987)
N. Verbiski, F. Beckett, O. Jerabek, W.J. Kolff, Pulsatile flow blood pump based on the principle of the Wankel engine. Preliminary report. The Journal of Thoracic and Cardiovascular Surgery. ,vol. 57, pp. 753- 756 ,(1969) , 10.1016/S0022-5223(19)42693-7
Yozu R, Harasaki H, Yada I, Jacobs G, Fujimoto Lk, Snow J, Olsen E, Sato N, Koike S, Golding Lr, PHYSIOPATHOLOGICAL STUDIES OF NONPULSATILE BLOOD FLOW IN CHRONIC MODELS. Asaio Journal. ,vol. 29, pp. 520- 525 ,(1983)
N. Mitsui, P. Havlik, J. Trinkl, T. Mesana, J. L. Demunck, J. R. Monties, I. Dion, B. Candelon, Control of pulsatile rotary pumps without pressure sensors. Asaio Journal. ,vol. 37, ,(1991)
Sekii H, Nakatani T, Akagi H, Tatsumi E, Goto M, Takano H, Taenaka Y, Sasaki E, Nakamura H, Yagura A, Physiologic reactions of awake animals to an immediate switch from a pulsatile to nonpulsatile systemic circulation. Asaio Journal. ,vol. 36, ,(1990)