ADC value and diffusion tensor imaging of prostate cancer: Changes in carbon-ion radiotherapy

作者: Yukihisa Takayama , Riwa Kishimoto , Shouhei Hanaoka , Hiroi Nonaka , Susumu Kandatsu

DOI: 10.1002/JMRI.21388

关键词: Effective diffusion coefficientMagnetic resonance imagingNuclear medicineMedicineProstateCarbon Ion RadiotherapyProstate cancerDiffusion MRIFractional anisotropyRadiation therapy

摘要: Purpose To assess the apparent diffusion coefficient (ADC) value and tensor image (DTI) including fractional anisotropy (FA) of noncancerous prostate cancer before after carbon-ion radiotherapy (CIRT). Materials Methods Nine patients with biopsy-proven underwent 1.5T magnetic resonance (MR) examinations. One patient benign prostatic hypertrophy one healthy volunteer were also examined as references. The changes in ADC values DTI entire calculated from b-values 0 700 (s/mm2) estimated between CIRT. Results ADC significantly increased CIRT by paired t-test (P < 0.01) but those inner gland (IG) peripheral zone (PZ) showed no significant change. By analysis variance, differences observed among IG PZ 0.05). After CIRT, had disappeared. FAs any comparisons. direction main axis CIRT. Conclusion There CIRT. They may be useful for monitoring structural under radiotherapy. J. Magn. Reson. Imaging 2008;27:1331–1335. © 2008 Wiley-Liss, Inc.

参考文章(15)
C D Petraki, C P Sfikas, Histopathological changes induced by therapies in the benign prostate and prostate adenocarcinoma. Histology and Histopathology. ,vol. 22, pp. 107- 118 ,(2007) , 10.14670/HH-22.107
Marc Van Cauteren, Taro Takahara, Tomohiro Yamashita, Seiei Yasuda, Yutaka Imai, Seiji Nasu, Diffusion weighted whole body imaging with background body signal suppression (DWIBS): technical improvement using free breathing, STIR and high resolution 3D display. Radiation Medicine. ,vol. 22, pp. 275- 282 ,(2004)
Tomohiro Nakayama, Kengo Yoshimitsu, Hiroyuki Irie, Hitoshi Aibe, Tsuyoshi Tajima, Kenji Shinozaki, Akihiro Nishie, Yoshiki Asayama, Daisuke Kakihara, Shuji Matsuura, Hiroshi Honda, Usefulness of the calculated apparent diffusion coefficient value in the differential diagnosis of retroperitoneal masses. Journal of Magnetic Resonance Imaging. ,vol. 20, pp. 735- 742 ,(2004) , 10.1002/JMRI.20149
Akihiro Tanimoto, Jun Nakashima, Hidaka Kohno, Hiroshi Shinmoto, Sachio Kuribayashi, Prostate cancer screening: The clinical value of diffusion-weighted imaging and dynamic MR imaging in combination with T2-weighted imaging Journal of Magnetic Resonance Imaging. ,vol. 25, pp. 146- 152 ,(2007) , 10.1002/JMRI.20793
Hirohiko Tsujii, Jun-etsu Mizoe, Tadashi Kamada, Masayuki Baba, Shingo Kato, Hirotoshi Kato, Hiroshi Tsuji, Shigeru Yamada, Shigeo Yasuda, Tatsuya Ohno, Takeshi Yanagi, Azusa Hasegawa, Toshiyuki Sugawara, Hidefumi Ezawa, Susumu Kandatsu, Kyosan Yoshikawa, Riwa Kishimoto, Tadaaki Miyamoto, Overview of clinical experiences on carbon ion radiotherapy at NIRS Radiotherapy and Oncology. ,vol. 73, pp. S41- S49 ,(2004) , 10.1016/S0167-8140(04)80012-4
Keiji Ogura, Shinya Maekawa, Kazutoshi Okubo, Yoshitaka Aoki, Takashi Okada, Kazushige Oda, Yuji Watanabe, Chotatsu Tsukayama, Yoichi Arai, Dynamic endorectal magnetic resonance imaging for local staging and detection of neurovascular bundle involvement of prostate cancer: Correlation with histopathologic results Urology. ,vol. 57, pp. 721- 726 ,(2001) , 10.1016/S0090-4295(00)01072-4
Roel A. M. Heesakkers, Jurgen J. Fütterer, Anke M. Hövels, Harrie C. M. van den Bosch, Tom W. J. Scheenen, Yvonne L. Hoogeveen, Jelle O. Barentsz, Prostate Cancer Evaluated with Ferumoxtran-10–enhanced T2*-weighted MR Imaging at 1.5 and 3.0 T: Early Experience Radiology. ,vol. 239, pp. 481- 487 ,(2006) , 10.1148/RADIOL.2392050411
Virendra Kumar, Naranamangalam R. Jagannathan, Rajeev Kumar, Sharat C. Das, Lokesh Jindal, Sanjay Thulkar, Siddhartha D. Gupta, Sadanand N. Dwivedi, Stefan Roell, Ashok K. Hemal, Narmada P. Gupta, Correlation between metabolite ratios and ADC values of prostate in men with increased PSA level Magnetic Resonance Imaging. ,vol. 24, pp. 541- 548 ,(2006) , 10.1016/J.MRI.2006.01.001
S White, H Hricak, R Forstner, J Kurhanewicz, D B Vigneron, C J Zaloudek, J M Weiss, P Narayan, P R Carroll, Prostate cancer: effect of postbiopsy hemorrhage on interpretation of MR images. Radiology. ,vol. 195, pp. 385- 390 ,(1995) , 10.1148/RADIOLOGY.195.2.7724756
C Pierpaoli, P Jezzard, P J Basser, A Barnett, G Di Chiro, Diffusion tensor MR imaging of the human brain. Radiology. ,vol. 201, pp. 637- 648 ,(1996) , 10.1148/RADIOLOGY.201.3.8939209