Τhe association of heart failure across left ventricular ejection fraction with mortality in atrial fibrillation.

摘要: AIMS The aim of this study is to investigate the prognostic implications presence heart failure (HF) across range left ventricular ejection fraction (LVEF) in patients with comorbid atrial fibrillation (AF). METHODS AND RESULTS We conducted a retrospective cohort 1063 (median age 76 years), discharged from cardiology ward primary or secondary diagnosis AF between 2015 and 2018. used Cox proportional-hazards spline models examine association HF, LVEF, outcome all-cause mortality. HF was documented 52.9% at baseline. During median follow-up 31 months (interquartile 10 52 months), 37.3% died. associated significantly higher risk mortality [adjusted hazard ratio (aHR) 2.17; 95% confidence interval (CI), 1.70 2.77; P < 0.001], which evident reduced (aHR 3.03; CI 2.41 4.52), mid-range 2.08; 1.47 2.94), preserved LVEF 1.94; 2.55). Among curve depicted non-linear death, there steep progressive increase for every 5% reduction below 25% 1.97, 1.04 3.73, P = 0.04). CONCLUSIONS In who were hospital, baseline independently twofold significant LVEF-classified subtypes. death rose as 25%.