Converting-enzyme in the choroid plexus, brain, and kidney: Immunocytochemical and biochemical studies in rats

作者: E. Rix , D. Ganten , B. Schüll , Th. Unger , R. Taugner

DOI: 10.1016/0304-3940(81)90075-6

关键词: AntibodyEnzymeAnatomyPathologyChoroid plexusBiologyBrush borderKidney

摘要: In rats, immunoreactivity was demonstrated in the brush border of choroid plexus, wall blood vessels brain, and proximal tubules kidney, using peroxidase-antiperoxidase technique (PAP) an anti-pulmonary converting-enzyme antibody. These findings correlate with biochemical data activity plexus other tissues. Possible functions enzyme relation to its localization are discussed.

参考文章(18)
Pierre Schelling, Detlev Ganten, Reiner Heckl, Karl Hayduk, Jeffrey S. Hutchinson, Gisbert Sponer, Ursula Ganten, ON THE ORIGIN OF ANGIOTENSIN-LIKE PEPTIDES IN CEREBROSPINAL FLUID Central Actions of Angiotensin and Related Hormones. pp. 519- 526 ,(1977) , 10.1016/B978-0-08-020933-3.50055-6
Rajko P. Igic, Carol J.G. Robinson, Ervin G. Erdös, ANGIOTENSIN I CONVERTING ENZYME ACTIVITY IN THE CHOROID PLEXUS AND IN THE RETINA Central Actions of Angiotensin and Related Hormones. pp. 23- 27 ,(1977) , 10.1016/B978-0-08-020933-3.50008-8
J M Conroy, H Hoffman, E S Kirk, H O Hirzel, E H Sonnenblick, R L Soffer, Pulmonary angiotensin-converting enzyme. Interspecies homology and inhibition by heterologous antibody in vivo. Journal of Biological Chemistry. ,vol. 251, pp. 4828- 4832 ,(1976) , 10.1016/S0021-9258(17)33190-3
P E Ward, E G Erdös, C D Gedney, R M Dowben, R C Reynolds, Isolation of membrane-bound renal enzymes that metabolize kinins and angiotensins. Biochemical Journal. ,vol. 157, pp. 643- 650 ,(1976) , 10.1042/BJ1570643
H.-Y. T. Yang, N. H. Neff, DISTRIBUTION AND PROPERTIES OF ANGIOTENSIN CONVERTING ENZYME OF RAT BRAIN Journal of Neurochemistry. ,vol. 19, pp. 2443- 2450 ,(1972) , 10.1111/J.1471-4159.1972.TB01298.X
Manjusri Das, Richard L. Soffer, Pulmonary angiotensin-converting enzyme antienzyme antibody. Biochemistry. ,vol. 15, pp. 5088- 5094 ,(1976) , 10.1021/BI00668A022
J.P. Swerts, R. Perdrisot, B. Malfroy, J.C. Schwartz, Is ‘enkephalinase” identical with ‘angiotensin-converting enzyme’? European Journal of Pharmacology. ,vol. 53, pp. 209- 210 ,(1979) , 10.1016/0014-2999(79)90167-5
P. Caldwell, B. Seegal, K. Hsu, M Das, R. Soffer, Angiotensin-converting enzyme: vascular endothelial localization Science. ,vol. 191, pp. 1050- 1051 ,(1976) , 10.1126/SCIENCE.175444
Alberto Arregui, Leslie L. Iversen, Angiotensin-converting enzyme: presence of high activity in choroid plexus of mammalian brain. European Journal of Pharmacology. ,vol. 52, pp. 147- 150 ,(1978) , 10.1016/0014-2999(78)90035-3