Distribution of the hypothalamic cardioactive hormone "G"-protein complex (PCG) in neuronal elements of the heart in intact and vagotomized rats.
作者： Silva S. Abrahamyan , Mariann Fodor , Armen A. Galoyan , Miklós Palkovits
关键词: Neuropeptide Y receptor 、 Internal medicine 、 Vagotomy 、 Endocrinology 、 Calcitonin 、 Neuropeptide 、 Biology 、 Calcitonin gene-related peptide 、 Ganglion 、 Immunohistochemistry 、 G protein
摘要: The distribution of the protein-carrier one coronary dilatatory glycopeptides, neurohormone “G” (PCG) in rat heart was examined by immunohistochemistry. PCG-immunoreactive nerve fibers and varicosities were found around cardiac ganglion cells close topographical contact with vessels capillaries heart. anatomical localization PCG-containing neuronal similar that calcitonin gene-related peptide (CGRP) neuropeptide Y (NPY); however, intensity stainings different. In contrast to NPY immunostainings, did not show any PCG immunoreactivity. Some small, SIF cell-like immunopositive neurons also immunostained PCG. atrial cardiomyocytes, only ANP exhibited fairly intensive Fourteen days after vagotomy, no considerable changes other neuropeptides investigated fibers. presence elements suggests a possible role this cardiovascular regulations.
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