Mechanism of lactic acid formation catalyzed by tetraamine rhodium(III) complexes

作者: Jette Eriksen , Ole Mønsted , Lene Mønsted

DOI: 10.1023/A:1006988916647

关键词: MethylglyoxalCatalysisMedicinal chemistryStereochemistryOrganometallic chemistryStoichiometryGlyceraldehydeChemistryRhodiumLactic acidLigand

摘要: The transformation of methylglyoxal and 1,3–dihydroxyacetone glyceraldehyde into lactic acid can be catalyzed by cis- tetraaminediaquarhodium(III) complexes ethane-1,2–diamine the macrocyclic racemic 5,5,7,12,12,14–hexamethyl-1,4,8,11– tetraazacyclotetradecane ligand. detailed stoichiometry this process has been investigated isotopic labelling studies 1H 13C-n.m.r. spectroscopy.

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