Crystal structure of rat biliverdin reductase.

作者： Akihiro Kikuchi , Sam-Yong Park , Hideyuki Miyatake , Danyu Sun , Michihiko Sato

DOI: 10.1038/84955

关键词: Biochemistry 、 Rossmann fold 、 Biliverdin 、 Oxidoreductase 、 Chemistry 、 Enzyme 、 Stereochemistry 、 Bilirubin 、 Biliverdin reductase 、 Electron donor 、 NAD+ kinase

摘要: … binding protein with one tightly bound Zn atom per protein … resulting electron density map was sufficiently clear to build … 295) of the 295-residue protein were disordered in the electron …

参考文章(26)

Axel T. Brünger, X-PLOR Version 3.1: A System for X-ray Crystallography and NMR ,(1992)

Mahin D. Maines, Bogdan V. Polevoda, Tian-Jun Huang, William K. Mccoubrey, Human biliverdin IXalpha reductase is a zinc-metalloprotein. Characterization of purified and Escherichia coli expressed enzymes. FEBS Journal. ,vol. 235, pp. 372- 381 ,(1996) , 10.1111/J.1432-1033.1996.00372.X

R.K. Kutty, M.D. Maines, Purification and characterization of biliverdin reductase from rat liver Journal of Biological Chemistry. ,vol. 256, pp. 3956- 3962 ,(1981) , 10.1016/S0021-9258(19)69552-9

Patrick J. Baker, K.Linda Britton, David W. Rice, Abdul Rob, Timothy J. Stillman, Structural consequences of sequence patterns in the fingerprint region of the nucleotide binding fold. Implications for nucleotide specificity. Journal of Molecular Biology. ,vol. 228, pp. 662- 671 ,(1992) , 10.1016/0022-2836(92)90848-E

William K. MCCOUBREY, Mahin D. MAINES, Site-directed mutagenesis of cysteine residues in biliverdin reductase. Roles in substrate and cofactor binding. FEBS Journal. ,vol. 222, pp. 597- 603 ,(1994) , 10.1111/J.1432-1033.1994.TB18902.X

T. Yamaguchi, Y. Komoda, H. Nakajima, Biliverdin-IX alpha reductase and biliverdin-IX beta reductase from human liver. Purification and characterization. Journal of Biological Chemistry. ,vol. 269, pp. 24343- 24348 ,(1994) , 10.1016/S0021-9258(19)51088-2

Raimo Tenhunen, Harvey S. Marver, Rudi Schmid, Microsomal Heme Oxygenase CHARACTERIZATION OF THE ENZYME Journal of Biological Chemistry. ,vol. 244, pp. 6388- 6394 ,(1969) , 10.1016/S0021-9258(18)63477-5

Eric de La Fortelle, Gérard Bricogne, [27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods Methods in Enzymology. ,vol. 276, pp. 472- 494 ,(1997) , 10.1016/S0076-6879(97)76073-7

Cornelia R. Bellamacina, The nicotinamide dinucleotide binding motif: a comparison of nucleotide binding proteins. The FASEB Journal. ,vol. 10, pp. 1257- 1269 ,(1996) , 10.1096/FASEBJ.10.11.8836039

A F McDonagh, L A Palma, R Schmid, Reduction of biliverdin and placental transfer of bilirubin and biliverdin in the pregnant guinea pig Biochemical Journal. ,vol. 194, pp. 273- 282 ,(1981) , 10.1042/BJ1940273