Metabolic factors in fatigue.

摘要: The supply of energy is fundamental importance for the ability to sustain exercise. maximal duration exercise negatively related relative intensity both during dynamic and static Since linearly rate utilisation this suggests that energetic deficiency plays a major role in aetiology muscle fatigue. Characteristic metabolic changes are generally observed at fatigue--the pattern being different after short term (lactate accumulation phosphocreatine depletion) from prolonged moderate (glycogen depletion). A common denominator fatigue these many other conditions reduced capacity generate ATP expressed by an increased catabolism adenine nucleotide pool fibre. Transient increases ADP suggested occur may be cause Experimental evidence human studies demonstrate near power output can attained acidotic conditions. Decreases pH therefore unlikely affect contractile machinery direct effect. However, acidosis interfere with possibly reducing glycolytic rate, could mechanism