Reduced Left Ventricular Torsion Early After Myocardial Infarction is Related to Left Ventricular Remodeling

摘要: Background— Left ventricular (LV) torsion is emerging as a sensitive parameter of LV systolic myocardial performance. The aim the present study was to explore effects acute infarction (AMI) on and determine value early after AMI in predicting remodeling at 6-month follow-up. Methods Results— A total 120 patients with first ST-segment elevation (mean±SD age, 59±10 years; 73% male) were included. All underwent primary percutaneous coronary intervention. After 48 hours, speckle-tracking echocardiography performed assess torsion; infarct size assessed by contrast echocardiography. At follow-up, volumes ejection fraction reassessed identity (defined ≥15% increase end-systolic volume). Compared control subjects, peak significantly impaired (1.54±0.64°/cm vs 2.07±0.27°/cm, P <0.001). By multivariate analysis, only ( β =0.36, <0.001) =−0.47, independently associated torsion. 19 showed remodeling. (odds ratio=0.77; 95% CI, 0.65–0.92; =0.003) ratio=1.04; 1.01–1.07; =0.021) related Peak provided modest but significant incremental over clinical, echocardiographic, variables receiver-operating characteristics curve ≤1.44°/cm highest sensitivity (95%) specificity (77%) predict remodeling. Conclusions— AMI. amount impairment predicts follow-up.