Pharmacokinetics of Neuroleptic Drugs and the Utility of Plasma Level Monitoring
作者： S. G. Dahl
DOI: 10.1007/978-3-642-73280-5_4
关键词: Patient compliance 、 Neuroleptic Drugs 、 Pharmacology 、 Clinical judgement 、 Receptor 、 Plasma levels 、 In vivo 、 Drug 、 Medicine 、 Pharmacokinetics
摘要: Variability in response to antipsychotic drug treatment may be caused by variable patient compliance, interactions with other drugs, pharmacokinetic variations and concentration-response relationships at the receptor level. Pharmacokinetic some cases compensated individual dosage adjustments based on plasma level measurements. The interpatient variability a certain time-course of concentrations site could hitherto only assessed clinical judgement. New methods for vivo assessment occupancy hold promise possible measurement parameters accounting least part interindividual variation
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