An Experimental and Modeling Study of the Viscoelastic Behavior of Collagen Gel

作者: Bin Xu , Haiyue Li , Yanhang Zhang

DOI: 10.1115/1.4024131

关键词: Biaxial tensile testComposite materialInverse Laplace transformViscoelasticityContinuous spectrumLaplace transformStress (mechanics)Relaxation (physics)Materials scienceStress relaxation

摘要: The macroscopic viscoelastic behavior of collagen gel was studied through relaxation time distribution spectrum obtained from stress tests and constitutive modeling. Biaxial were performed to characterize the crosslinked with Genipin solution. Relaxation data by inverse Laplace transform. Peaks at short (0.3 s-1 s), medium (3 s-90 long (>200 s) observed in continuous spectrum, which likely correspond mechanisms involve fiber, inter-fibril, fibril sliding. intensity long-term peaks increases higher initial levels indicating engagement fibrils tissue strain. We have shown that can be well simulated using a model viscous material parameters directly spectrum. Results current study suggest is useful connecting macro-level matrices micro-level structure changes.

参考文章(21)
Michael S. Sacks, Biaxial Mechanical Evaluation of Planar Biological Materials Journal of Elasticity. ,vol. 61, pp. 199- 246 ,(2001) , 10.1023/A:1010917028671
Yu Zou, Yanhang Zhang, The orthotropic viscoelastic behavior of aortic elastin. Biomechanics and Modeling in Mechanobiology. ,vol. 10, pp. 613- 625 ,(2011) , 10.1007/S10237-010-0260-4
Navdeep Singh Sodhi, Tomoko Sasaki, Zhan-Hui Lu, Kaoru Kohyama, Phenomenological viscoelasticity of some rice starch gels Food Hydrocolloids. ,vol. 24, pp. 512- 517 ,(2010) , 10.1016/J.FOODHYD.2009.12.009
Jessica E. Wagenseil, Tetsuro Wakatsuki, Ruth J. Okamoto, George I. Zahalak, Elliot L. Elson, One-dimensional viscoelastic behavior of fibroblast populated collagen matrices. Journal of Biomechanical Engineering-transactions of The Asme. ,vol. 125, pp. 719- 725 ,(2003) , 10.1115/1.1614818
H.S. Gupta, J. Seto, S. Krauss, P. Boesecke, H.R.C. Screen, In situ multi-level analysis of viscoelastic deformation mechanisms in tendon collagen. Journal of Structural Biology. ,vol. 169, pp. 183- 191 ,(2010) , 10.1016/J.JSB.2009.10.002
Stephanie R Toms, Greg J Dakin, Jack E Lemons, Alan W Eberhardt, Quasi-linear viscoelastic behavior of the human periodontal ligament. Journal of Biomechanics. ,vol. 35, pp. 1411- 1415 ,(2002) , 10.1016/S0021-9290(02)00166-5