Distortion product otoacoustic emissions test is useful in children undergoing cisplatin treatment.
作者： René Toral-Martiñón , Paul Shkurovich-Bialik , Miguel Angel Collado-Corona , Ignacio Mora-Magaña , Shani Goldgrub-Listopad
DOI: 10.1016/S0188-4409(03)00022-5
关键词: Hearing loss 、 Pure tone audiometry 、 Ototoxicity 、 Diagnostic Specificity 、 Adverse effect 、 Audiology 、 Distortion product 、 Assessment methods 、 Cisplatin 、 Medicine
摘要: Abstract Background. Cisplatin is a widely used chemotherapy agent that has several adverse effects, such as ototoxicity. Evaluation of hearing loss due to cisplatin therapy in children difficult. The purpose this study was compare the validity distortion product otoacoustic emissions (DPOAEs) with pure tone audiometry (PTA) assessing under therapy. Methods. We reviewed files 26 aged between 2 and 15 years; 14 were girls. All treatment for malignancy. PTA DPOAEs obtained at same session. Three subjects studied twice; thus, there 29 sets studies. Results. Determining cut-off point 45 dB HL 4 SPL difference DPOAEs, diagnostic specificity latter 0.97 while sensitivity 0.57. Conclusions. represent highly valuable test evaluating treatment. quick objective assessment method not requiring much cooperation from children.
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