Oxygen free radicals in ischemic acute renal failure in the rat.

作者: M S Paller , J R Hoidal , T F Ferris

DOI: 10.1172/JCI111524

关键词: BiochemistryEndocrinologyIschemiaLipid peroxidationXanthine oxidaseRenal ischemiaInternal medicineRenal glomerulusKidneyRenal blood flowChemistryLipid peroxide

摘要: … oxidase generates superoxide radical (O-) as a reduction product of … of the treated SOD to inhibit superoxide-mediated reduction of … Inactivated SOD provided no protection against the …

参考文章(33)
Frega Ns, Guertler B, Leaf A, DiBona Dr, Ischemic renal injury. Kidney International. ,vol. 6, ,(1976)
Pietronigro Dd, Flamm Es, Demopoulos Hb, Seligman Ml, The free radical pathology and the microcirculation in the major central nervous system disorders. Acta Physiologica Scandinavica. ,vol. 492, pp. 91- 119 ,(1980)
Leon M Dorfman, Gerald E Adams, Reactivity of the Hydroxyl Radical in Aqueous Solutions. National Bureau of Standards. ,(1973) , 10.6028/NBS.NSRDS.46
Dale A. Parks, Gregory B. Bulkley, D.Neil Granger, Stanley R. Hamilton, Joe M. McCord, Ischemic injury in the cat small intestine: Role of superoxide radicals Gastroenterology. ,vol. 82, pp. 9- 15 ,(1982) , 10.1016/0016-5085(82)90115-9
D.Neil Granger, Gianfranco Rutili, Joe M. McCord, Superoxide radicals in feline intestinal ischemia Gastroenterology. ,vol. 81, pp. 22- 29 ,(1981) , 10.1016/0016-5085(81)90648-X
I. Fridovich, Quantitative Aspects of the Production of Superoxide Anion Radical by Milk Xanthine Oxidase Journal of Biological Chemistry. ,vol. 245, pp. 4053- 4057 ,(1970) , 10.1016/S0021-9258(18)62884-4
Wolfgang J. Mergner, Mary A. Smith, Benjamin F. Trump, Studies on the pathogenesis of ischemic cell injury Experimental and Molecular Pathology. ,vol. 26, pp. 1- 12 ,(1977) , 10.1016/0014-4800(77)90062-4
EW Kellogg, I Fridovich, Superoxide, hydrogen peroxide, and singlet oxygen in lipid peroxidation by a xanthine oxidase system. Journal of Biological Chemistry. ,vol. 250, pp. 8812- 8817 ,(1975) , 10.1016/S0021-9258(19)40745-X
Stuart L. Linas, David Dickmann, Mechanism of the decreased renal blood flow in the potassium-depleted conscious rat Kidney International. ,vol. 21, pp. 757- 764 ,(1982) , 10.1038/KI.1982.94
Collan Yrjo, Myong Won Kahng, Benjamin F. Trump, Mary W. Smith, Changes in mitochondrial lipids of rat kidney during ischemia Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. ,vol. 618, pp. 192- 201 ,(1980) , 10.1016/0005-2760(80)90025-9