GDF15/MIC-1 Functions As a Protective and Antihypertrophic Factor Released From the Myocardium in Association With SMAD Protein Activation
作者： Jian Xu , Thomas R Kimball , John N Lorenz , David A Brown , Asne R Bauskin
DOI: 10.1161/01.RES.0000202804.84885.D0
关键词: Dilated cardiomyopathy 、 GDF15 、 SMAD 、 Pressure overload 、 Heart failure 、 Autocrine signalling 、 Transforming growth factor 、 Endocrinology 、 Muscle hypertrophy 、 Internal medicine 、 Biology
摘要: Here we identified growth-differentiation factor 15 (GDF15) (also known as MIC-1), a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic …
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sci-hub.se 参考文章(40)
Tao Liu, Asne R Bauskin, John Zaunders, David A Brown, Susan Pankurst, Pamela J Russell, Samuel N Breit, None, Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells. Cancer Research. ,vol. 63, pp. 5034- 5040 ,(2003)
Beverly H. Lorell, Blase A. Carabello, Left Ventricular Hypertrophy Pathogenesis, Detection, and Prognosis Circulation. ,vol. 102, pp. 470- 479 ,(2000) , 10.1161/01.CIR.102.4.470
S. L. Milgram, O. Smithies, N. Maeda, P. M. Oliver, J. E. Fox, R. Kim, H. A. Rockman, H.-S. Kim, R. L. Reddick, K. N. Pandey, Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A Proceedings of the National Academy of Sciences of the United States of America. ,vol. 94, pp. 14730- 14735 ,(1997) , 10.1073/PNAS.94.26.14730
Srinivasa Subramaniam, Jens Strelau, Klaus Unsicker, Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways. Journal of Biological Chemistry. ,vol. 278, pp. 8904- 8912 ,(2003) , 10.1074/JBC.M210037200
Christophe Depre, Gregory L. Shipley, Wenhao Chen, Qiuying Han, Torsten Doenst, Meredith L. Moore, Stanislaw Stepkowski, Peter J.A. Davies, Heinrich Taegtmeyer, Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy Nature Medicine. ,vol. 4, pp. 1269- 1275 ,(1998) , 10.1038/3253
Jeffery D. Molkentin, A friend within the heart: natriuretic peptide receptor signaling Journal of Clinical Investigation. ,vol. 111, pp. 1275- 1277 ,(2003) , 10.1172/JCI18389
Rita Holtwick, Martin van Eickels, Boris V. Skryabin, Hideo A. Baba, Alexander Bubikat, Frank Begrow, Michael D. Schneider, David L. Garbers, Michaela Kuhn, Pressure-independent cardiac hypertrophy in mice with cardiomyocyte-restricted inactivation of the atrial natriuretic peptide receptor guanylyl cyclase-A Journal of Clinical Investigation. ,vol. 111, pp. 1399- 1407 ,(2003) , 10.1172/JCI17061
Robyn L Woods, CARDIOPROTECTIVE FUNCTIONS OF ATRIAL NATRIURETIC PEPTIDE AND B‐TYPE NATRIURETIC PEPTIDE: A BRIEF REVIEW Clinical and Experimental Pharmacology and Physiology. ,vol. 31, pp. 791- 794 ,(2004) , 10.1111/J.0305-1870.2004.04073.X
Michele Albertoni, Phillip H Shaw, Michimasa Nozaki, Sophie Godard, Mirna Tenan, Marie-France Hamou, Douglas W Fairlie, Samuel N Breit, Vishwas M Paralkar, Nicolas de Tribolet, Erwin G Van Meir, Monika E Hegi, None, Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1 Oncogene. ,vol. 21, pp. 4212- 4219 ,(2002) , 10.1038/SJ.ONC.1205610
Rik Derynck, Ying E. Zhang, Smad-dependent and Smad-independent pathways in TGF-β family signalling Nature. ,vol. 425, pp. 577- 584 ,(2003) , 10.1038/NATURE02006