Genetic Strategies in Biological Psychiatry

作者: Ronald O Rieder , Elliot S Gershon

DOI: 10.1001/ARCHPSYC.1978.01770310072005

关键词: DiathesisIdentification (biology)SchizophreniaSocial environmentVulnerabilityClinical psychologyHomogeneousPsychologyResearch strategiesPsychiatryBiological psychiatry

摘要: • Studies of the etiology schizophrenia and other psychiatric illnesses may be executed by using a genetic framework in experimental design. This article describes research strategies for identifying factors that produce vulnerability to illness. The proposed evaluate role given factor comparing transmission this within pedigrees In biologically heterogeneous disorder, these can used identify homogeneous subgroups. report also strategy identification environmental events promote development illness, either independently or conjunction with diathesis.

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