Caries experience in children with various genetic sensitivity levels to the bitter taste of 6-n-propylthiouracil (PROP): a pilot study.
作者： Brent P J Lin
DOI:
关键词: Bitter taste 、 Analysis of variance 、 Taste 、 Dentistry 、 Caries experience 、 Supertaster 、 Propylthiouracil 、 Medicine 、 Linear regression 、 Dentition
摘要: PURPOSE The objective of this pilot study was to determine the prevalence coronal dental caries among children with different genetic sensitivity levels taste, as determined by 6-n-propylthiouracil (PROP). METHODS Coronal and restorations in permanent primary dentition were evaluated 150 healthy school-aged aged 6 12 years. A filter paper containing used each subject's ability taste bitter sweet substances. Supertasters perceived stronger tastes from a variety substances than both medium tasters nontasters. data analyzed ANOVA Duncan's multiple range test, Mantel-Haenszel chi-square, linear regression analyses, Pearson's coefficient correlation. RESULTS nontasters had more mean decayed, missing, filled surfaces (dfs/DMFS) tasters. values decayed (ds/DS) significantly higher tasters, compared supertasters. After adjusting for missing teeth, expressed percentage available surfaces, significant differences dfs/DMFS ds/DS persisted (r = -0.49, P < .001 r -0.51, .0001 respectively). CONCLUSIONS all associated factors controlled, only independent variable related overall experience. results suggested an increased experience nontaster children.
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