Regulation of gene expression by nucleosomes
作者： John Svaren , Wolfram Hörz
DOI: 10.1016/S0959-437X(96)80046-3
关键词: Histone 、 Cell biology 、 DNA-binding protein 、 Heterochromatin formation 、 Saccharomyces cerevisiae 、 Biology 、 Nucleosome 、 Regulation of gene expression 、 Psychological repression 、 Genetics 、 Developmental biology
摘要: During the past year, characterization of mechanisms and factors capable disrupting nucleosomes during transcriptional activation has been a recurrent theme in studies which address contribution nucleosome structure to gene regulation. In vivo using yeast Drosophila together with biochemical purification schemes perturbation assays have provided evidence for existence multiprotein complexes that are able alleviate repression. At same time, new insights into mechanism heterochromatin formation gained, direct links structure.
elsevier.com
sci-hub.se 参考文章(62)
J. Svaren, J. Schmitz, W. Hörz, The transactivation domain of Pho4 is required for nucleosome disruption at the PHO5 promoter. The EMBO Journal. ,vol. 13, pp. 4856- 4862 ,(1994) , 10.1002/J.1460-2075.1994.TB06812.X
U. Venter, J. Svaren, J. Schmitz, A. Schmid, W. Hörz, A nucleosome precludes binding of the transcription factor Pho4 in vivo to a critical target site in the PHO5 promoter. The EMBO Journal. ,vol. 13, pp. 4848- 4855 ,(1994) , 10.1002/J.1460-2075.1994.TB06811.X
Virginia A. Zakian, 5 Saccharomyces Telomeres: Function, Structure, and Replication Cold Spring Harbor Monograph Archive. ,vol. 29, pp. 107- 137 ,(1995) , 10.1101/087969457.29.107
J. S. Platero, T. Hartnett, J. C. Eissenberg, Functional analysis of the chromo domain of HP1. The EMBO Journal. ,vol. 14, pp. 3977- 3986 ,(1995) , 10.1002/J.1460-2075.1995.TB00069.X
L. Trieschmann, P.J. Alfonso, M.P. Crippa, A.P. Wolffe, M. Bustin, Incorporation of chromosomal proteins HMG-14/HMG-17 into nascent nucleosomes induces an extended chromatin conformation and enhances the utilization of active transcription complexes. The EMBO Journal. ,vol. 14, pp. 1478- 1489 ,(1995) , 10.1002/J.1460-2075.1995.TB07134.X
K. Ura, J. J. Hayes, A. P. Wolffe, A positive role for nucleosome mobility in the transcriptional activity of chromatin templates: restriction by linker histones. The EMBO Journal. ,vol. 14, pp. 3752- 3765 ,(1995) , 10.1002/J.1460-2075.1995.TB00045.X
G. Wall, P.D. Varga-Weisz, R. Sandaltzopoulos, P.B. Becker, Chromatin remodeling by GAGA factor and heat shock factor at the hypersensitive Drosophila hsp26 promoter in vitro. The EMBO Journal. ,vol. 14, pp. 1727- 1736 ,(1995) , 10.1002/J.1460-2075.1995.TB07162.X
D. Zink, R. Paro, Drosophila Polycomb-group regulated chromatin inhibits the accessibility of a trans-activator to its target DNA. The EMBO Journal. ,vol. 14, pp. 5660- 5671 ,(1995) , 10.1002/J.1460-2075.1995.TB00253.X
L. P. O'Neill, B. M. Turner, Histone H4 acetylation distinguishes coding regions of the human genome from heterochromatin in a differentiation-dependent but transcription-independent manner. The EMBO Journal. ,vol. 14, pp. 3946- 3957 ,(1995) , 10.1002/J.1460-2075.1995.TB00066.X
M. Truss, J. Bartsch, A. Schelbert, R.J. Haché, M. Beato, Hormone induces binding of receptors and transcription factors to a rearranged nucleosome on the MMTV promoter in vivo. The EMBO Journal. ,vol. 14, pp. 1737- 1751 ,(1995) , 10.1002/J.1460-2075.1995.TB07163.X