A Diet with Carbohydrates Eaten Primarily at Dinner: An Innovative, Nutritional Approach to End the Vicious Cycle of Abdominal Obesity

摘要: Sustained weight reduction is needed in order to end the “vicious cycle” of abdominal obesity—a known risk factor for diabetes and coronary heart disease. However, most obese subjects fail maintain long-term diets; they regain lost body develop metabolic syndrome. Adipose tissue itself contributes cycling pathology, since it functions as an endocrine organ. Fat cells synthesize secrete adipocytokines that regulate hunger satiety, well impact insulin resistance, syndrome, inflammation. The idea studying effect a low-calorie diet with carbohydrates eaten primarily at dinner came about after analyzing results from research Muslim populations during Ramadan. For month Ramadan, Muslims fast day consume carbohydrate-rich meal sundown. This dramatically modifies diurnal pattern leptin secretion. Our experimental improved secretion patterns “satiety hormone,” leptin, “hunger ghrelin, adiponectin—“the link between obesity, resistance syndrome.” Lower scores greater improvements anthropometric, biochemical, inflammatory parameters were observed compared controls. We believe this novel nutritional approach should be considered first line treatment, prior pharmaceutical or surgical interventions.