MAPLE Fabricated Fe3O4@Cinnamomum verum Antimicrobial Surfaces for Improved Gastrostomy Tubes
作者： Alina Anghel , Alexandru Grumezescu , Mariana Chirea , Valentina Grumezescu , Gabriel Socol
DOI: 10.3390/MOLECULES19078981
关键词: Analytical chemistry 、 Biocompatibility 、 Maple 、 Nuclear chemistry 、 Cinnamomum 、 Gram-positive bacteria 、 Nanoparticle 、 Cinnamomum verum 、 Chemistry 、 Antibacterial activity 、 Coating
摘要: Cinnamomum verum-functionalized Fe3O4 nanoparticles of 9.4 nm in size were laser transferred by matrix assisted pulsed evaporation (MAPLE) technique onto gastrostomy tubes (G-tubes) for antibacterial activity evaluation toward Gram positive and negative microbial colonization. X-ray diffraction analysis the nanoparticle powder showed a polycrystalline magnetite structure, whereas infrared mapping confirmed integrity C. verum (CV) functional groups after transfer. The specific topography deposited films involved uniform thin coating together with several aggregates bio-functionalized particles covering G-tubes. Cytotoxicity assays an increase G-tube surface biocompatibility Fe3O4@CV treatment, allowing normal development endothelial cells up to five days incubation. Microbiological on nanoparticle-modified surfaces have proved improvement anti-adherent properties, significantly reducing both bacteria
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