Measurement of total RBC volume relative to lean body mass for diagnosis of polycythemia.

作者: Nathaniel I. Berlin , S. Mitchell Lewis

DOI: 10.1309/KP4E-MBUY-VGT7-HMAV

关键词: Body waterAnimal scienceEndocrinologyObesityTotal body water measurementKilogramBody densityBody weightVolume (thermodynamics)Lean body massInternal medicineMedicine

摘要: An elevated total RBC volume (TRCV) in milliliters per kilogram of body weight has been an essential criterion for determining whether a person is polycythemic. This may be misleading obese subjects as the TRCV fat only one-tenth that lean mass (LBM). Various formulas based on surface area have used to account this difference, but they are not always reliable. Direct measurement was obtained originally studies which composition determined by combined density and water method. impractical routine procedure, simple-to-use instruments now available direct person’s percentage impedance technology. Thus, can discounts effects fat, graph designed normalize LBM. The men women established 36 mL/kg LBM; when it more than 43 LBM, diagnosis polycythemia made with confidence.

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