Acute blood pressure responses in healthy adults during controlled air pollution exposures.

作者: Bruce Urch , Frances Silverman , Paul Corey , Jeffrey R. Brook , Karl Z. Lukic

DOI: 10.1289/EHP.7785

关键词: Blood pressurePhysiologyOzoneAir pollutionHeart ratePotential riskParticulatesInhalation exposureChemistrySystemic hemodynamics

摘要: Exposure to air pollution has been shown cause arterial vasoconstriction and alter autonomic balance. Because these biologic responses may influence systemic hemodynamics, we investigated the effect of on blood pressure (BP). Responses during 2-hr exposures concentrated ambient fine particles (particulate matter or = 0.27). These findings suggest that exposure environmentally relevant concentrations PM2.5 O3 rapidly increases DBP. The magnitude BP change is associated with carbon content. vehicular traffic provide a common link between our observations previous studies in which was identified as potential risk factor for cardiovascular disease.

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